Enhanced antibacterial performance of ultrathin silver/platinum nanopatches by a sacrificial anode mechanism

Abuayyash, A. and Ziegler, N. and Meyer, H. and Meischein, M. and Sengstock, C. and Moellenhoff, J. and Rurainsky, C. and Heggen, M. and Garzón-Manjón, A. and Scheu, C. and Tschulik, K. and Ludwig, Al. and Köller, M.

Volume: 24 Pages:
DOI: 10.1016/j.nano.2019.102126
Published: 2020

The development of antibacterial implant surfaces is a challenging task in biomaterial research. We fabricated a highly antibacterial bimetallic platinum (Pt)/silver(Ag) nanopatch surface by short time sputtering of Pt and Ag on titanium. The sputter process led to a patch-like distribution with crystalline areas in the nanometer-size range (1.3–3.9 nm thickness, 3–60 nm extension). Structural analyses of Pt/Ag samples showed Ag- and Pt-rich areas containing nanoparticle-like Pt deposits of 1–2 nm. The adhesion and proliferation properties of S. aureus on the nanopatch samples were analyzed. Consecutively sputtered Ag/Pt nanopatches (Pt followed by Ag) induced enhanced antimicrobial activity compared to co-sputtered Pt/Ag samples or pure Ag patches of similar Ag amounts. The underlying sacrificial anode mechanism was proved by linear sweep voltammetry. The advantages of this nanopatch coating are the enhanced antimicrobial activity despite a reduced total amount of Ag/Pt and a self-limited effect due the rapid Ag dissolution. © 2019 Elsevier Inc.

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